Season
- Season 16 2008-09-02
- Season 15 2007-09-04
- Season 14 2006-09-05
- Season 13 2005-09-06
- Season 12 2004-08-31
- Season 11 2003-09-03
- Season 10 2002-09-03
- Season 9 2001-09-04
- Season 8 2000-09-05
- Season 7 1999-09-07
- Season 6 1998-09-15
- Season 5 1997-09-09
- Season 4 1996-09-17
- Season 3 1995-09-11
- Season 2 1994-09-12
- Season 1 1993-09-13
- Season 0 1996-09-12
Episode
- Episode 1: Christina Applegate, Artie Lange, 30 Seconds To Mars
- Episode 2: Samuel L. Jackson, Richard Lewis, Brad Paisley
- Episode 3: John Lithgow, Eugene Levy, Flight Of The Conchords
- Episode 4: Elijah Wood, Michael Rapaport, Brian Regan
- Episode 5: Gwyneth Paltrow, Peter Falk, Switchfoot
- Episode 6: Anthony Hopkins, Caroline Rhea, Mick Foley
- Episode 7: Sacha Baron Cohen, Liev Schreiber, Jim Gaffigan
- Episode 8: Lara Flynn Boyle, Steve Schirripa, The New Pornographers
- Episode 9: Jason Lee, Harland Williams, Jimeoin
- Episode 10: Ice-T, Erika Christensen, Steve Winwood
- Episode 11: Kim Cattrall, Seth Meyers, David Rakoff
- Episode 12: Ricky Gervais, Stephen King, Nickel Creek
- Episode 13: Martha Stewart, Big Show, Death Cab For Cutie
- Episode 14: Matt Leblanc, Amanda Bynes, Jud Hale
- Episode 15: Jessica Alba, Jeff Garlin, Sheryl Crow
- Episode 16: Tiger Woods, Amy Poehler, Against Me
- Episode 17: Freddie Prinze, Jr., Jennifer Esposito, Matt Pond, Pa
- Episode 18: Matthew Mcconaughey, Jesse Eisenberg, Greg Behrendt
- Episode 19: U2
- Episode 20: Jon Heder, Jessica Biel, Nada Surf
- Episode 21: Rosie O'donnell, Chris Elliott, Jamie Cullum
- Episode 22: Charlize Theron, Cameron Crowe, Tariq "king Flex" Nasheed.
- Episode 23: Darrell Hammond, Jason Schwartzman, My Morning Jacket
- Episode 24: Dolly Parton, Molly Sims
- Episode 25: John Leguizamo, Joy Behar, Dungen
- Episode 26: James Woods, Joy Behar, Shawn King
- Episode 27: Val Kilmer, Gabrielle Union, Mark Leyner
- Episode 28: Dwayne "the Rock" Johnson, Andrea Mitchell, Ric Ocasek
- Episode 29: Brian Williams, Susie Essman, Neil Young
- Episode 30: Philip Seymour Hoffman, John Krasinski, Neil Young
- Episode 31: Jake Gyllenhaal, Neil Young
- Episode 32: David Spade, Xzibit, Neil Young
- Episode 33: Jennifer Aniston, 50 Cent, Dan Naturman
- Episode 34: Robert Downey, Jr., Steve Irwin, Allison Krauss & Union Station
- Episode 35: Keira Knightley, Nicole Richie, Green Day
- Episode 36: Reese Witherspoon, Jon Favreau, Kevin Brennan
- Episode 37: Rosario Dawson, Steve Harvey, Big & Rich
- Episode 38: Joaquin Phoenix, Sarah Silverman, Trey Anastasio
- Episode 39: Patricia Heaton, Ryan Reynolds, Alanis Morissette
- Episode 40: Usher, Colin Quinn, Pink Martini
- Episode 41: Peter Gallagher, Rainn Wilson, Demetri Martin
- Episode 42: Al Franken, Lake Bell, Ray Davies
- Episode 43: Jerry Lewis, Finesse Mitchell, Gogol Bordello
- Episode 44: Tom Arnold, Brian Seltzer Orchestra
- Episode 45: Naomi Watts, The Magic Numbers
- Episode 46: Alan Alda, Billy Joel
- Episode 47: Gisele Bundchen, Dane Cook, The White Stripes
- Episode 48: Adrien Brody, Anthony Anderson, Patti Smith
- Episode 49: Lindsay Lohan, Colin Hanks, Coldplay
- Episode 50: Luke Wilson, Jack Klugman, Ghost Hunters Jason Hawes & Grant Wilson
- Episode 51: Tina Fey, William Moseley, James Blunt
- Episode 52: Heidi Klum, Carson Kressley, Jake Shimabukuro
- Episode 53: Donald Trump, Emily Mortimer, Susan Tedeschi
- Episode 54: Jack Black, Rachel McAdams, Charles Ross
- Episode 55: Barbara Walters, Bill Hader, Clap Your Hands Say Yeah
- Episode 56: Jim Carrey, Isaac Hayes
- Episode 57: Tea Leoni, Patton Oswalt, Doris Kearns Goodwin
- Episode 58: Johnny Knoxville, Tucker Carlson, Tony Bennett
- Episode 59: Matthew Broderick, Bonnie Hunt, John Mayer Trio
- Episode 60: Quentin Tarantino, Nick Swardson, John Legend
- Episode 61: Seth Green, Andy Serkis, Rodney Crowell & Emmylou Harris
- Episode 62: Paul Giamatti, Allen Covert, Tom Papa
- Episode 63: Alan Cumming, Sarah Chalke, Living Things
- Episode 64: LL Cool J, Mo Rocca, Jimmy Carr
- Episode 65: Terrence Howard, John Daly, O.A.R.
- Episode 66: Chazz Palminteri, Emily Procter, J.W. Hart
- Episode 67: Will Arnett, Chris Parnell, Flipsyde
- Episode 68: Martin Lawrence, Eliza Dushku, Soweto Gospel Choir
- Episode 69: Josh Lucas, Marc Maron, Jen Chapin
- Episode 70: Kate Beckinsale, Brian Posehn, Metric
- Episode 71: Clyde Peeling, Nia Long, The Fray
- Episode 72: Anthony Hopkins, Piper Perabo, Marty Stuart & His Fabulous Superlatives
- Episode 73: Bob Saget, James Carville, Yellowcard
- Episode 74: Emma Thompson, Jason Priestley, Norah Vincent
- Episode 75: Steve Carell, Sanaa Lathan, Lewis Taylor
- Episode 76: Benjamin Bratt, Andy Samberg, Broken Social Scene
- Episode 77: Meredith Vieiera, Jeff Probst, Jim Gaffigan
- Episode 78: Bette Midler, David Gregory
- Episode 79: Stephen Colbert, Rick Moranis, Sarah Vowell
- Episode 80: Harrison Ford, Amy Adams, K.T. Tunstall
- Episode 81: Tom Cavanagh, Josh Holloway, Sigur Ros
- Episode 82: Nicolette Sheridan, Steve Coogan, Aimee Mann
- Episode 83: Rachel Weisz, Paul Bettany, Graham Bensinger
- Episode 84: Bruce Willis, Mary Lynn Rajskub, Dropkick Murphys
- Episode 85: Gisele Bundchen, Bill Bellamy, Belle & Sebastian
- Episode 86: Bob Costas, Jenna Fischer, Dwayne Perkins
- Episode 87: Alec Baldwin, Fred Goss, The Derek Trucks Band
- Episode 88: Sarah Jessica Parker, Matisyahu
- Episode 89: Matthew McConaughey, Kristin Davis, James Hunter
- Episode 90: Salma Hayek, Eric Balfour, Street Drum Corps
- Episode 91: Conan goes to Finland
- Episode 92: Vin Diesel, Jamie Lynn DiScala, We Are Scientists
- Episode 93: Martha Stewart, Macaulay Culkin, Billy Bragg
- Episode 94: Amanda Peet, Bradley Cooper, Greg Fitzsimmons
- Episode 95: Lorraine Bracco, Steve Harvey, Jaheim
- Episode 96: Queen Latifah, Tim Gunn, Richard Ashcroft
- Episode 97: Ray Romano, Sue Johanson, José González
- Episode 98: Josh Hartnett, Paget Brewster, Editors
- Episode 99: Antonio Banderas, Seth Meyers, The Little Willies
- Episode 100: Amy Poehler, Steven Schirripa, She Wants Revenge
- Episode 101: Lucy Liu, Jon Lovitz, "Beer Hunter" Michael Jackson
- Episode 102: Nathan Lane, Padma Lakshmi, Kris Kristofferson
- Episode 103: Jeff Daniels, Rachael Ray, Fiona Apple
- Episode 104: Hank Azaria, Mimi Rogers, Pink
- Episode 105: David Schwimmer, Patton Oswalt, Melissa Cross
- Episode 106: Jarod Miller, Regina Hall, Teddy Thompson
- Episode 107: Julia Louis-Dreyfus, Jason Sudeikis, Daniel Powter
- Episode 108: Mandy Moore, Alexis Bledel, Secret Machines
- Episode 109: Darrell Hammond, Reggie Bush, Eagles of Death Metal
- Episode 110: Howie Mandel, Jim Gaffigan, The Goo Goo Dolls
- Episode 111: Paul Rudd, Robert Smigel, Chris Klein, Hawthorne Heights
- Episode 112: Jeff Goldblum, Jodelle Ferland, Taking Back Sunday
- Episode 113: Jeremy Piven, Jim Cramer, The Strokes
- Episode 114: Tom Hanks, Wolfmother
- Episode 115: Edward Norton, Izabel Goulart, Gene Pompa
- Episode 116: Sean Hayes, Cheap Trick
- Episode 117: Dave Chappelle, Common
- Episode 118: John C. Reilly, Vlasta, John Mayer
- Episode 119: Barack Obama, Wilco
- Episode 120: Megan Mullally, Mike Wallace, Jewel
- Episode 121: Brian Williams, Jorge Garcia, People in Planes
- Episode 122: Edie Falco, Billy Connolly, The Raconteurs
- Episode 123: Larry King, Omar Epps, Sheila Kelley
- Episode 124: Seth Green, Lee Evans, Atmosphere
- Episode 125: Hugh Jackman, Tim Russert, Gnarls Barkley
- Episode 126: Jennifer Aniston, Harold Perrineau, Victor Varnado
- Episode 127: Halle Berry, Anderson Cooper, Peeping Tom
- Episode 128: The Best Of Chicago
- Episode 129: Eric McCormack,Famke Janssen & Drive-By Truckers
- Episode 130: Luke Perry, Ludacris, Van Hunt
- Episode 131: Kevin Kline, Kevin Dillon, Lewis Black
- Episode 132: Denis Leary, Rita Wilson, Brandi Carlile
- Episode 133: Julia Stiles, Louis C.K., Be Your Own Pet
- Episode 134: Rosie Perez, Morgan Pressel, Regina Spektor
- Episode 135: Dane Cook, Shaun White, Dr. John
- Episode 136: Sandra Oh, Gordon Ramsay, Chris Isaak
- Episode 137: Alan Cumming, Henry Winkler, All-American Rejects
- Episode 138: Adam Sandler, John Cena, The Subways
- Episode 139: Kate Beckinsale, Tyrese Gibson, iceberg climber Will Gadd
- Episode 140: Thomas Haden Church, Bruce Springsteen
- Episode 141: Hilary Duff, Neil Patrick Harris, Bonnie Raitt
- Episode 142: Kevin Spacey, Todd Barry, Strays Don't Sleep
- Episode 143: Orlando Bloom, Campbell Brown, Cheap Trick
- Episode 144: Kate Bosworth, Tom Everett Scott, Arj Barker
- Episode 145: Marlon Wayans, Brian Posehn, Elvis Costello & Allen Toussaint
- Episode 146: Stephen Colbert, Rainn Wilson, Lil' Ed & The Blues Imperials
- Episode 147: Paul Reubens, Carlos Mencia, David Lee Roth
- Episode 148: Owen Wilson, Kerry Washington, Tom Papa
- Episode 149: Rosario Dawson, Kevin Pollak, Matthew Sweet & Susanna Hoffs
- Episode 150: Luke Wilson, Bryce Dallas Howard, Los Lonely Boys
- Episode 151: Uma Thurman, Kevin Smith, The New York Dolls
- Episode 152: Al Gore, Paul Giamatti, Beastie Boys
- Episode 153: Will Ferrell, Christopher Meloni, Landon Pigg
- Episode 154: John C. Reilly, Ashanti, Jackie Greene
- Episode 155: Ice-T, Tim Gunn, Body Count
- Episode 156: Martin Short, Kirk "Sticky Fingaz" Jones, Ziggy Marley
- Episode 157: Darrell Hammond, Christina Milian, Yeah Yeah Yeahs
- Episode 158: Heidi Klum, Justin Long, Sonic Youth
- Episode 159: Matt Dillon, Jonah Hill, Guster
- Episode 160: Kevin Nealon, Morgan Spurlock, Josh Ritter
- Episode 161: Donald Trump, Marc Maron, Ray LaMontagne
- Episode 162: Jarod Miller, Mary Birdsong, Neko Case
Late Night with Conan O'Brien Season 13 Dane Cook, Shaun White, Dr. John
Stepping into the late-late slot vacated by David Letterman, Conan O'Brien stars in a show that far outdoes its competition in sheer strangeness. Along with the celebrity interviews and musical numbers typical of late-night talk shows, this program make frequent use of odd walk-on characters and frequent "visits" from celebrity guests.
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